Scientific scope
- Atom-level enzyme design
- Active-site scaffolding
- Functional protein design
RFdiffusion2
Moved the RFdiffusion lineage from backbone-first generation toward atom-level functional design.
Model familyRFdiffusion
OrganizationInstitute for Protein Design, UW
Release year2025
Version2
AccessOpen source
CheckpointResearch release / project terms
LicenseOpen source
Source typedeveloper
Capabilities added
- Atom-level conditioning for enzyme active sites
- More direct functional-site design
Model lineage
Related releases in the same family.
current
RFdiffusion2
Moved the RFdiffusion lineage from backbone-first generation toward atom-level functional design.
superseded
RFdiffusion
Converted a structure-prediction lineage into a generative protein-design system.