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Versioned registry · current

ProteinMPNN

Made sequence design a practical downstream step after backbone generation.

Model familyProteinMPNN / LigandMPNN
OrganizationInstitute for Protein Design, UW
Release year2022
Versionprotein inverse folding
AccessOpen source
CheckpointPublic research checkpoints
LicenseMIT
Source typepeer-reviewed

Scientific scope

  • Protein sequence design from backbone

Capabilities added

  • Fast graph-based inverse folding
Model lineage

Related releases in the same family.

current-companion

LigandMPNN

Extended the ProteinMPNN concept to functional sites and molecular partners.

current

ProteinMPNN

Made sequence design a practical downstream step after backbone generation.