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Versioned registry · current

ESM3

Unified sequence, structure and functional annotations in one generative model family.

Model familyESM3
OrganizationEvolutionaryScale (now CZ Biohub)
Release year2024
Versionmultimodal generative
AccessLimited open access
CheckpointOpen and hosted variants under separate terms
LicenseESM3-open (non-commercial) + commercial API
Source typepeer-reviewed

Scientific scope

  • Protein sequence
  • Protein structure
  • Protein function

Capabilities added

  • Joint multimodal generation and completion
Model lineage

Related releases in the same family.

current

ESM3

Unified sequence, structure and functional annotations in one generative model family.